EU global human rights sanctions regime: is the genie out of the bottle?

GWAS of Diabetic Nephropathy: Is the GENIE out of the Bottle?

Diabetic nephropathy (DN) is associated with excess morbidity and mortality, in both type 1 (T1D) and type 2 (T2D) diabetic patients. Despite intensification of treatment, DN remains a growing problem worldwide [1–6]. In 2009, treatment of diabetic end stage renal disease patients accounted for approximately 40% of the US$43 billion expended for dialysis treatment in the United States New manag...

The gene is out of the bottle.

Stem cells are not proarrhythmic: letting the genie out of the bottle.

Ischemic heart disease remains a leading cause of mortality worldwide. Myocardial infarction (MI) accounts for more than half of cardiovascular-related deaths.1 With rising numbers of surviving MI patients and an aging population, congestive heart failure has become a major health concern, with symptomatic patients having a poorer prognosis.2 Despite substantial advances in medical and device s...

Are we letting the genie out of the bottle by diagnosing (classifying) Fibromyalgia in RA?

The study by Wolfe et al. in this issue of PAIN is the first observation of the development of fibromyalgia (FM) in a cohort of patients [11]. They examined rates and predictors of onset of FM in patients with rheumatoid arthritis (RA). To define FM, they used the new American College of Rheumatology (ACR) 2010 criteria that allow better tracking of FM status over time compared to the previous,...

Is stem cell therapy proarrhythmic? Stem Cells Are Not Proarrhythmic Letting the Genie out of the Bottle

Ischemic heart disease remains a leading cause of mortality worldwide. Myocardial infarction (MI) accounts for more than half of cardiovascular-related deaths.1 With rising numbers of surviving MI patients and an aging population, congestive heart failure has become a major health concern, with symptomatic patients having a poorer prognosis.2 Despite substantial advances in medical and device s...